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In this anabolic process, the upregulation of renal insulin-like growth factor 1 (IGF-1) plays a key role, which has inspired numerous studies considering the potential regenerative actions of the IGF-1 and the subsequent increase in the glomerular filtration rate

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Speers AB, Brandes MS, Kedjejian NE, Matthews DG, Caruso M, Wright KM, et al

Four patients did not complete MRI scanning, and ten patients were excluded owing to excessive head motion